Major depressive disorder 40-60 mg daily. Generalized anxiety disorder Adult 60 mg daily. Elderly Initially 30 mg once daily for 2 wk, may be increased to target dose of 60 mg thereafter. Max dose: 120 mg/day. Diabetic peripheral neuropathic pain 60 mg once daily. Fibromyalgia & chronic musculoskeletal pain Initially 30 mg once daily for 1 wk, may be increased to target & max dose of 61 mg once daily thereafter.

May be taken with or without food: Swallow whole, do not chew/crush. Do not open the cap or sprinkle its contents on food or mix w/ liqd.